检测编号：SS0610149

服务项目

境象生物为您提供GATA3基因的突变检测服务。

样本要求

新鲜或石蜡包埋的病理组织样本（≥100mg组织）

服务周期

合同签订后30个工作日。

报告结果

服务报告包含检测基因、检出位点、基因型、是否发生突变、突变等位基因频率等结果。

检测方法

测序法

基因信息

基因名称	基因全名	基因位置	外显子个数	CDS长度
GATA3	GATA binding protein 3	10p15	6	约3070 bp
基因摘要	This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009].

相关文献

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2. Gao YB et al, Genetic landscape of esophageal squamous cell carcinoma., Nature genetics;46(10):1097-102, 2014, PubMed Link
3. Giannakis M et al, RNF43 is frequently mutated in colorectal and endometrial cancers., Nature genetics;46(12):1264-6, 2014, PubMed Link
4. Lee YS et al, Genomic profile analysis of diffuse-type gastric cancers., Genome biology;15(4):R55, 2014, PubMed Link
5. Martin D et al, The head and neck cancer cell oncogenome: A platform for the development of precision molecular therapies., Oncotarget, 2014, PubMed Link