large intestine cancer(大肠癌)

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检测编号:SS0690238


服务项目

境象生物为您提供MSH2基因的突变检测服务。

样本要求

新鲜或石蜡包埋的病理组织样本(≥100mg组织)

服务周期

合同签订后30个工作日。

报告结果

服务报告包含检测基因、检出位点、基因型、是否发生突变、突变等位基因频率等结果。

检测方法

测序法

基因信息

基因名称基因全名基因位置外显子个数 CDS长度
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 2p21 17 约3209 bp
基因摘要 This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

相关文献

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