lung cancer(肺癌)

返回

检测编号:SS0710484


服务项目

境象生物为您提供PDE4DIP基因的突变检测服务。

样本要求

新鲜或石蜡包埋的病理组织样本(≥100mg组织)

服务周期

合同签订后30个工作日。

报告结果

服务报告包含检测基因、检出位点、基因型、是否发生突变、突变等位基因频率等结果。

检测方法

测序法

基因信息

基因名称基因全名基因位置外显子个数 CDS长度
PDE4DIP phosphodiesterase 4D interacting protein 1q12 46 约8143 bp
基因摘要 The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010].

相关文献

  1. Arai E et al, Multilayer-omics analysis of renal cell carcinoma, including the whole exome, methylome and transcriptome., International journal of cancer. Journal international du cancer;135(6):1330-42, 2014, PubMed Link
  2. Aydin IT et al, FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm., Journal of the National Cancer Institute;106(6):dju107, 2014, PubMed Link
  3. Bruno A et al, Mutational analysis of primary central nervous system lymphoma., Oncotarget;5(13):5065-75, 2014, PubMed Link
  4. Gao YB et al, Genetic landscape of esophageal squamous cell carcinoma., Nature genetics;46(10):1097-102, 2014, PubMed Link
  5. Giannakis M et al, RNF43 is frequently mutated in colorectal and endometrial cancers., Nature genetics;46(12):1264-6, 2014, PubMed Link