芯片介绍

hsa-miR-217 miRNA靶基因表达谱PCR芯片精心选 择了hsa-miR-217 miRNA 可能的88个靶基因，采用精心设计和反复验证过的引物，运用实时荧光PCR方法帮您寻找miRNA真正的靶基因。应用2块靶基因PCR芯片分别对实验组和对照组样品进行分析，寻找表达有差异的基因，即可确定该miRNA的靶基因。如果您需要更改miRNA靶基因列表中的基因，也可以联系我们。

基因功能分类

根据Gene Ontology功能数据库和KEGG生物通路数据库对88个靶基因进行分类。

RNA splicing, via transesterification reactions ( GO:0000375 ):

SRSF10, HNRNPA3, HNRNPH2, PAPOLA, SRSF11, SMC1A, YTHDC1

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile ( GO:0000377 ):

SRSF10, HNRNPA3, HNRNPH2, PAPOLA, SRSF11, SMC1A, YTHDC1

nuclear mRNA splicing, via spliceosome ( GO:0000398 ):

SRSF10, HNRNPA3, HNRNPH2, PAPOLA, SRSF11, SMC1A, YTHDC1

chromatin organization ( GO:0006325 ):

ASF1A, HLTF, SIRT1, SUZ12, TLK1

transcription ( GO:0006350 ):

ASF1A, CBFB, CREBZF, DR1, ELK3, HIF1A, HLTF, KHDRBS1, NAB1, PAPOLA, PHF20, PHTF2, PSIP1, RBM39, RYBP, SFPQ, SIRT1, SLTM, SMAD2, SUZ12, TCF12, ZEB1, MED13, VEZF1, YY1, ZMYND11

regulation of transcription from RNA polymerase II promoter ( GO:0006357 ):

CBFB, DR1, HIF1A, HLTF, MTDH, RYBP, SIRT1, SMAD2, SUZ12, TCF12, ZEB1, MED13, VEZF1, YY1, ZMYND11

RNA processing ( GO:0006396 ):

LUC7L3, SRSF10, HNRNPA3, HNRNPH2, KHDRBS1, PAPOLA, QKI, RBM39, SFPQ, SRSF11, SMAD2, SMC1A, SYNCRIP, YTHDC1

mRNA processing ( GO:0006397 ):

LUC7L3, SRSF10, HNRNPA3, HNRNPH2, KHDRBS1, PAPOLA, QKI, RBM39, SFPQ, SRSF11, SMC1A, SYNCRIP, YTHDC1

protein folding ( GO:0006457 ):

CANX, RANBP2, ST13, VBP1

nucleocytoplasmic transport ( GO:0006913 ):

SRSF10, AGFG1, MAPK1, RANBP2

anti-apoptosis ( GO:0006916 ):

BNIP3L, MCL1, SON

response to DNA damage stimulus ( GO:0006974 ):

ATMIN, ASF1A, CUL4B, MAPK1, PPP1CB, SFPQ, SIRT1, SMC1A, TDG, TLK1

cell cycle ( GO:0007049 ):

CD2AP, CUL5, EIF4G2, KHDRBS1, MAPK1, PAFAH1B1, PPP1CB, SEPT7, SMC1A, STAG2, TLK1, ZMYND11

protein localization ( GO:0008104 ):

CANX, G3BP2, LIN7C, MAPK1, PIKFYVE, RANBP2, RDX, SCAMP1, TLK1, SEC62, TMED10, ZDHHC17

RNA splicing ( GO:0008380 ):

LUC7L3, SRSF10, HNRNPA3, HNRNPH2, PAPOLA, QKI, RBM39, SFPQ, SRSF11, SMC1A, SYNCRIP, YTHDC1

macromolecule catabolic process ( GO:0009057 ):

ADAM9, CD2AP, CUL5, DCP2, FBXO11, FBXO28, FBXW2, HLTF, RANBP2, RNF11, RNF138, TDG, THRB, UBE2E3, UBE2G1, WSB1, YME1L1

negative regulation of biosynthetic process ( GO:0009890 ):

CREBZF, DR1, ELK3, KHDRBS1, MTDH, NAB1, RYBP, SIRT1, SMAD2, SUZ12, ZEB1, ZMYND11

posttranscriptional regulation of gene expression ( GO:0010608 ):

EIF4G2, MAPK1, NCK1, QKI, SMAD2, SYNCRIP

negative regulation of gene expression ( GO:0010629 ):

BNIP3L, CREBZF, DR1, ELK3, KHDRBS1, MTDH, NAB1, RYBP, SIRT1, SMAD2, SUZ12, ZEB1, ZMYND11

protein transport ( GO:0015031 ):

CANX, LIN7C, MAPK1, RANBP2, SCAMP1, TLK1, SEC62, TMED10, ZDHHC17

membrane organization ( GO:0016044 ):

GNAI3, KRAS, PAFAH1B1, PIKFYVE, SCAMP1

mRNA metabolic process ( GO:0016071 ):

LUC7L3, DCP2, SRSF10, HNRNPA3, HNRNPH2, KHDRBS1, PAPOLA, QKI, RBM39, SFPQ, SRSF11, SMC1A, SYNCRIP, YTHDC1

negative regulation of transcription ( GO:0016481 ):

CREBZF, DR1, ELK3, KHDRBS1, MTDH, NAB1, RYBP, SIRT1, SMAD2, SUZ12, ZEB1, ZMYND11

chromatin modification ( GO:0016568 ):

ASF1A, HLTF, SIRT1, SUZ12, TLK1

modification-dependent protein catabolic process ( GO:0019941 ):

CD2AP, CUL4B, CUL5, FBXO11, FBXO28, FBXW2, HLTF, RANBP2, RNF11, RNF138, THRB, UBE2E3, UBE2G1, WSB1

protein catabolic process ( GO:0030163 ):

ADAM9, CD2AP, CUL4B, CUL5, FBXO11, FBXO28, FBXW2, HLTF, RANBP2, RNF11, RNF138, THRB, UBE2E3, UBE2G1, WSB1, YME1L1

regulation of cell migration ( GO:0030334 ):

ADAM9, CLIC4, HIF1A, MAPK1

N-terminal protein amino acid modification ( GO:0031365 ):

NAA50

regulation of Ras GTPase activity ( GO:0032318 ):

ACAP2, ASAP2, AGFG1, PAFAH1B1

cellular response to stress ( GO:0033554 ):

ATMIN, ASF1A, CCDC47, CUL4B, HIF1A, MAPK1, PPP1CB, SFPQ, SIRT1, SMC1A, TDG, TLK1

cellular protein localization ( GO:0034613 ):

MAPK1, PIKFYVE, RANBP2, TLK1, SEC62

negative regulation of apoptosis ( GO:0043066 ):

BNIP3L, KRAS, MCL1, SON

negative regulation of programmed cell death ( GO:0043069 ):

BNIP3L, KRAS, MCL1, SON

regulation of GTPase activity ( GO:0043087 ):

ACAP2, ASAP2, AGFG1, PAFAH1B1

modification-dependent macromolecule catabolic process ( GO:0043632 ):

CD2AP, CUL4B, CUL5, FBXO11, FBXO28, FBXW2, HLTF, RANBP2, RNF11, RNF138, THRB, UBE2E3, UBE2G1, WSB1

cellular protein catabolic process ( GO:0044257 ):

ADAM9, CD2AP, CUL4B, CUL5, FBXO11, FBXO28, FBXW2, HLTF, RANBP2, RNF11, RNF138, THRB, UBE2E3, UBE2G1, WSB1

cellular macromolecule catabolic process ( GO:0044265 ):

ADAM9, CD2AP, CUL5, DCP2, FBXO11, FBXO28, FBXW2, HLTF, RANBP2, RNF11, RNF138, TDG, THRB, UBE2E3, UBE2G1, WSB1

establishment of protein localization ( GO:0045184 ):

CANX, LIN7C, MAPK1, RANBP2, SCAMP1, TLK1, SEC62, TMED10, ZDHHC17

maintenance of protein location ( GO:0045185 ):

G3BP2

intracellular transport ( GO:0046907 ):

SRSF10, AGFG1, MAPK1, PAFAH1B1, PIKFYVE, RANBP2, RHOT1, SCAMP1, TLK1, SEC62, TMED10

nuclear transport ( GO:0051169 ):

SRSF10, AGFG1, MAPK1, RANBP2

negative regulation of nitrogen compound metabolic process ( GO:0051172 ):

CREBZF, DR1, ELK3, SRSF10, KHDRBS1, MTDH, NAB1, RYBP, SIRT1, SMAD2, SUZ12, ZEB1, ZMYND11

maintenance of location ( GO:0051235 ):

G3BP2

regulation of cell motion ( GO:0051270 ):

ADAM9, CLIC4, HIF1A, MAPK1

positive regulation of cell motion ( GO:0051272 ):

ADAM9, HIF1A, MAPK1

chromosome organization ( GO:0051276 ):

ASF1A, HLTF, SIRT1, SMC1A, SUZ12, TLK1

proteolysis involved in cellular protein catabolic process ( GO:0051603 ):

ADAM9, CD2AP, CUL4B, CUL5, FBXO11, FBXO28, FBXW2, HLTF, RANBP2, RNF11, RNF138, THRB, UBE2E3, UBE2G1, WSB1

negative regulation of cell death ( GO:0060548 ):

BNIP3L, KRAS, MCL1, SON

cellular macromolecule localization ( GO:0070727 ):

MAPK1, PIKFYVE, RANBP2, TLK1, SEC62

Glycerophospholipid metabolism ( hsa00564 ):

LYPLA1

Spliceosome ( hsa03040 ):

SRSF10, HNRNPA3

ErbB signaling pathway ( hsa04012 ):

KRAS, MAPK1, NCK1

Chemokine signaling pathway ( hsa04062 ):

GNAI3, KRAS, MAPK1, RAP1B

Ubiquitin mediated proteolysis ( hsa04120 ):

CUL5, UBE2E3, UBE2G1

Endocytosis ( hsa04144 ):

ASAP2, PIKFYVE

mTOR signaling pathway ( hsa04150 ):

HIF1A, MAPK1

TGF-beta signaling pathway ( hsa04350 ):

MAPK1, SMAD2

Focal adhesion ( hsa04510 ):

MAPK1, PPP1CB, RAP1B

Adherens junction ( hsa04520 ):

MAPK1, SMAD2, YES1

Fc epsilon RI signaling pathway ( hsa04664 ):

KRAS, MAPK1

Fc gamma R-mediated phagocytosis ( hsa04666 ):

ASAP2, MAPK1, PIKFYVE

Neurotrophin signaling pathway ( hsa04722 ):

KRAS, MAPK1, RAP1B

Regulation of actin cytoskeleton ( hsa04810 ):

KRAS, MAPK1, PIKFYVE, PPP1CB, RDX

Pathways in cancer ( hsa05200 ):

HIF1A, KRAS, MAPK1, SMAD2

Colorectal cancer ( hsa05210 ):

KRAS, MAPK1, SMAD2

Renal cell carcinoma ( hsa05211 ):

HIF1A, KRAS, MAPK1, RAP1B

Pancreatic cancer ( hsa05212 ):

KRAS, MAPK1, SMAD2

Glioma ( hsa05214 ):

KRAS, MAPK1

Prostate cancer ( hsa05215 ):

KRAS, MAPK1

Bladder cancer ( hsa05219 ):

KRAS, MAPK1

Chronic myeloid leukemia ( hsa05220 ):

KRAS, MAPK1

Acute myeloid leukemia ( hsa05221 ):

KRAS, MAPK1

Non-small cell lung cancer ( hsa05223 ):

KRAS, MAPK1