芯片介绍

hsa-miR-302d miRNA靶基因表达谱PCR芯片精心选 择了hsa-miR-302d miRNA 可能的88个靶基因，采用精心设计和反复验证过的引物，运用实时荧光PCR方法帮您寻找miRNA真正的靶基因。应用2块靶基因PCR芯片分别对实验组和对照组样品进行分析，寻找表达有差异的基因，即可确定该miRNA的靶基因。如果您需要更改miRNA靶基因列表中的基因，也可以联系我们。

基因功能分类

根据Gene Ontology功能数据库和KEGG生物通路数据库对88个靶基因进行分类。

mitotic cell cycle ( GO:0000278 ):

CUL3, CUL5, PSMC6, SMC1A, SMC4, TAF2, UBA3

DNA metabolic process ( GO:0006259 ):

ASF1A, PURA, SIRT1, SLK, SMC1A, SUMO1, TMX1

DNA replication ( GO:0006260 ):

PURA, SIRT1, TMX1

chromatin organization ( GO:0006325 ):

ARID4B, ASF1A, CHD1, KDM3A, NR3C1, SIRT1, SUV420H1, SUZ12, TBL1XR1, TLK1

chromatin assembly or disassembly ( GO:0006333 ):

ARID4B, ASF1A, CHD1

transcription ( GO:0006350 ):

ARID4B, ASF1A, BCLAF1, DR1, KDM3A, NCOA2, NR3C1, PAPOLA, PHF20, PURA, RB1CC1, RYBP, SIRT1, SP3, SUV420H1, SUZ12, TBL1XR1, TCERG1, VEZF1, ZNF238

regulation of transcription from RNA polymerase II promoter ( GO:0006357 ):

CHD1, DR1, MTDH, NCOA2, RYBP, SIRT1, SUZ12, TBL1XR1, VEZF1, ZNF238

proteolysis ( GO:0006508 ):

ADAM9, CUL3, CUL5, DPP8, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

ubiquitin-dependent protein catabolic process ( GO:0006511 ):

CUL3, CUL5, UBR5, FBXO11, PCNP, PSMC6, TBL1XR1, USP34

endocytosis ( GO:0006897 ):

PIKFYVE, ACAP2, PIKFYVE

apoptosis ( GO:0006915 ):

BNIP3L, MCL1, ROCK1, RYBP, SIRT1, SLK

anti-apoptosis ( GO:0006916 ):

BNIP3L, MCL1, SON, TMX1, YWHAZ

induction of apoptosis ( GO:0006917 ):

BCLAF1, BNIP3L, CUL3, CUL5

cell cycle ( GO:0007049 ):

CALM1, CUL3, CUL5, ERBB2IP, PCNP, PSMC6, RB1CC1, SMC1A, SMC4, TAF2, TLK1, UBA3, SMC1A, YWHAZ

enzyme linked receptor protein signaling pathway ( GO:0007167 ):

ADAM9, EPS8, ERBB2IP, ZFYVE16

transforming growth factor beta receptor signaling pathway ( GO:0007179 ):

ADAM9

intracellular signaling cascade ( GO:0007242 ):

ADAM9, ARHGAP29, ARL8B, UBR5, KDM3A, NCOA2, NR3C1, PIKFYVE, RAB21, RAB6A, RAPGEF2, RB1CC1, ROCK1, SMC1A, SPAG9, TLK1

protein localization ( GO:0008104 ):

ARFIP1, ERBB2IP, PIKFYVE, RAB21, RDX, SEC23A, SRP9, VAMP7, TLK1, VPS13C, XPO1, YWHAZ, ZDHHC17, ZFYVE16

cell death ( GO:0008219 ):

BNIP3L, MCL1, ROCK1, RYBP, SIRT1, SLK, TMEM123

macromolecule catabolic process ( GO:0009057 ):

ADAM9, CUL3, CUL5, DCP2, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

negative regulation of biosynthetic process ( GO:0009890 ):

BCLAF1, DR1, MTDH, NCOA2, PURA, RYBP, SIRT1, SRP9, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

positive regulation of biosynthetic process ( GO:0009891 ):

ASF1A, KDM3A, NCOA2, RNF6, TBL1XR1, TMX1

response to organic substance ( GO:0010033 ):

ADAM9, EPS8, KDM3A, MCL1, NR3C1

membrane invagination ( GO:0010324 ):

PIKFYVE

positive regulation of macromolecule biosynthetic process ( GO:0010557 ):

ASF1A, KDM3A, NCOA2, RNF6, TBL1XR1, TMX1

negative regulation of macromolecule biosynthetic process ( GO:0010558 ):

BCLAF1, DR1, MTDH, NCOA2, PURA, RYBP, SIRT1, SRP9, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

positive regulation of macromolecule metabolic process ( GO:0010604 ):

ADAM9, ASF1A, KDM3A, NCOA2, PSMC6, RB1CC1, RNF6, TBL1XR1, TMX1

negative regulation of macromolecule metabolic process ( GO:0010605 ):

BCLAF1, BNIP3L, DR1, SRSF10, MTDH, NCOA2, PSMC6, PURA, RYBP, SIRT1, SRP9, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

positive regulation of gene expression ( GO:0010628 ):

ASF1A, KDM3A, NCOA2, TAF2, TBL1XR1, TMX1

negative regulation of gene expression ( GO:0010629 ):

BCLAF1, BNIP3L, DR1, MTDH, NCOA2, PURA, RYBP, SIRT1, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

regulation of cell death ( GO:0010941 ):

ADAM9, BCLAF1, BNIP3L, CUL3, CUL5, MCL1, NR3C1, RB1CC1, ROCK1, SIRT1, SON, TMX1, YWHAZ

positive regulation of cell death ( GO:0010942 ):

BCLAF1, BNIP3L, CUL3, CUL5, NR3C1

programmed cell death ( GO:0012501 ):

BNIP3L, MCL1, ROCK1, RYBP, SIRT1, SLK

induction of programmed cell death ( GO:0012502 ):

BCLAF1, BNIP3L, CUL3, CUL5

protein transport ( GO:0015031 ):

ARFIP1, ERBB2IP, RAB21, SEC23A, SRP9, VAMP7, TLK1, XPO1, YWHAZ, ZDHHC17, ZFYVE16

membrane organization ( GO:0016044 ):

PIKFYVE, SEC23A

vesicle organization ( GO:0016050 ):

VAMP7, ZFYVE16

mRNA metabolic process ( GO:0016071 ):

DCP2, SRSF10, HNRNPA3, HNRNPH3, MBNL1, PAPOLA, QKI, SERBP1, SF3B1, SMC1A, YTHDC1

vesicle-mediated transport ( GO:0016192 ):

PIKFYVE, RAB6A, SEC23A, VAMP7, TMX1, YWHAZ, ZFYVE16

endosome transport ( GO:0016197 ):

PIKFYVE, VAMP7, ZFYVE16

death ( GO:0016265 ):

BNIP3L, MCL1, ROCK1, RYBP, SIRT1, SLK, TMEM123

negative regulation of transcription ( GO:0016481 ):

BCLAF1, DR1, MTDH, NCOA2, PURA, RYBP, SIRT1, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

chromatin modification ( GO:0016568 ):

ASF1A, CHD1, KDM3A, NR3C1, SIRT1, SUV420H1, SUZ12, TBL1XR1, TLK1

regulation of phosphate metabolic process ( GO:0019220 ):

ADAM9, IBTK, PPP1R2, RB1CC1, SPAG9

modification-dependent protein catabolic process ( GO:0019941 ):

CUL3, CUL5, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

cell cycle process ( GO:0022402 ):

CUL3, CUL5, PSMC6, SMC1A, SMC4, TAF2

cell cycle phase ( GO:0022403 ):

CUL3, CUL5, SMC1A, SMC4, TAF2

protein catabolic process ( GO:0030163 ):

ADAM9, CUL3, CUL5, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

steroid hormone receptor signaling pathway ( GO:0030518 ):

UBR5, KDM3A, NCOA2, NR3C1

intracellular receptor-mediated signaling pathway ( GO:0030522 ):

UBR5, KDM3A, NCOA2, NR3C1

negative regulation of cellular biosynthetic process ( GO:0031327 ):

BCLAF1, DR1, MTDH, NCOA2, PURA, RYBP, SIRT1, SRP9, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

positive regulation of cellular biosynthetic process ( GO:0031328 ):

ASF1A, KDM3A, NCOA2, RNF6, TBL1XR1, TMX1

protein modification by small protein conjugation ( GO:0032446 ):

FBXL5, FBXO11, FBXO3, PCNP, SUMO1, SUZ12

cellular response to stress ( GO:0033554 ):

ASF1A, UBR5, RB1CC1, SIRT1, SLK, SMC1A, SUMO1, TLK1

cellular protein localization ( GO:0034613 ):

ARFIP1, ERBB2IP, PIKFYVE, SEC23A, SRP9, TLK1, XPO1, YWHAZ, ZFYVE16

regulation of cell proliferation ( GO:0042127 ):

CD164, CUL3, CUL5, PRKRIR, PURA, SIRT1, SUZ12

regulation of apoptosis ( GO:0042981 ):

ADAM9, BCLAF1, BNIP3L, CUL3, CUL5, MCL1, NR3C1, RB1CC1, ROCK1, SIRT1, SON, TMX1, YWHAZ

positive regulation of apoptosis ( GO:0043065 ):

BCLAF1, BNIP3L, CUL3, CUL5, NR3C1

negative regulation of apoptosis ( GO:0043066 ):

BNIP3L, MCL1, RB1CC1, ROCK1, SON, TMX1, YWHAZ

regulation of programmed cell death ( GO:0043067 ):

ADAM9, BCLAF1, BNIP3L, CUL3, CUL5, MCL1, NR3C1, RB1CC1, ROCK1, SIRT1, SON, TMX1, YWHAZ

positive regulation of programmed cell death ( GO:0043068 ):

BCLAF1, BNIP3L, CUL3, CUL5, NR3C1

negative regulation of programmed cell death ( GO:0043069 ):

BNIP3L, MCL1, RB1CC1, ROCK1, SON, TMX1, YWHAZ

modification-dependent macromolecule catabolic process ( GO:0043632 ):

CUL3, CUL5, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

cellular protein catabolic process ( GO:0044257 ):

ADAM9, CUL3, CUL5, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

cellular macromolecule catabolic process ( GO:0044265 ):

ADAM9, CUL3, CUL5, DCP2, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

establishment of protein localization ( GO:0045184 ):

ARFIP1, ERBB2IP, RAB21, SEC23A, SRP9, VAMP7, TLK1, XPO1, YWHAZ, ZDHHC17, ZFYVE16

regulation of transcription ( GO:0045449 ):

ARID4B, ASF1A, BCLAF1, CHD1, DR1, SRSF10, KDM3A, MTDH, NCOA2, NR3C1, PHF20, PURA, RB1CC1, RNF6, RYBP, SIRT1, SP3, SUMO1, SUV420H1, SUZ12, TBL1XR1, TCERG1, TMX1, UBA3, VEZF1, ZNF238

negative regulation of transcription, DNA-dependent ( GO:0045892 ):

DR1, MTDH, NCOA2, PURA, RYBP, SIRT1, SUZ12, TBL1XR1, ZNF238

positive regulation of transcription, DNA-dependent ( GO:0045893 ):

ASF1A, NCOA2, TAF2, TBL1XR1, TMX1

negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic pro ( GO:0045934 ):

BCLAF1, DR1, SRSF10, MTDH, NCOA2, PURA, RYBP, SIRT1, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic pro ( GO:0045935 ):

ASF1A, KDM3A, NCOA2, RNF6, TBL1XR1, TMX1

positive regulation of transcription ( GO:0045941 ):

ASF1A, KDM3A, NCOA2, TAF2, TBL1XR1, TMX1

intracellular transport ( GO:0046907 ):

ARFIP1, ERBB2IP, SRSF10, PIKFYVE, SEC23A, SRP9, VAMP7, TLK1, TMX1, XPO1, YWHAZ, ZFYVE16

negative regulation of nitrogen compound metabolic process ( GO:0051172 ):

BCLAF1, DR1, SRSF10, MTDH, NCOA2, PURA, RYBP, SIRT1, SUMO1, SUZ12, TBL1XR1, UBA3, ZNF238

positive regulation of nitrogen compound metabolic process ( GO:0051173 ):

ASF1A, KDM3A, NCOA2, RNF6, TBL1XR1, TMX1

regulation of phosphorus metabolic process ( GO:0051174 ):

ADAM9, IBTK, PPP1R2, RB1CC1, SPAG9

regulation of RNA metabolic process ( GO:0051252 ):

ASF1A, CHD1, DR1, SRSF10, MBNL1, MTDH, NCOA2, NR3C1, PURA, RNF6, RYBP, SERBP1, SIRT1, SP3, SUZ12, TBL1XR1, TMX1, VEZF1, ZNF238

negative regulation of RNA metabolic process ( GO:0051253 ):

DR1, SRSF10, MTDH, NCOA2, PURA, RYBP, SIRT1, SUZ12, TBL1XR1, ZNF238

positive regulation of RNA metabolic process ( GO:0051254 ):

ASF1A, NCOA2, TAF2, TBL1XR1, TMX1

chromosome organization ( GO:0051276 ):

ARID4B, ASF1A, CHD1, KDM3A, NR3C1, SIRT1, SMC1A, SMC4, SUV420H1, SUZ12, TBL1XR1, TLK1

cell division ( GO:0051301 ):

ROCK1, SMC1A, SMC4

interphase ( GO:0051325 ):

CUL3, CUL5, TAF2

interphase of mitotic cell cycle ( GO:0051329 ):

CUL3, CUL5, TAF2

proteolysis involved in cellular protein catabolic process ( GO:0051603 ):

ADAM9, CUL3, CUL5, UBR5, FBXL5, FBXO11, FBXO3, FBXW2, MARCH7, PCNP, PSMC6, RNF6, SUMO1, TBL1XR1, UBA3, UBE2J1, USP34

negative regulation of cell death ( GO:0060548 ):

BNIP3L, MCL1, RB1CC1, ROCK1, SON, TMX1, YWHAZ

protein modification by small protein conjugation or removal ( GO:0070647 ):

FBXL5, FBXO11, FBXO3, PCNP, SUMO1, SUZ12

cellular macromolecule localization ( GO:0070727 ):

ARFIP1, ERBB2IP, PIKFYVE, SEC23A, SRP9, TLK1, XPO1, YWHAZ, ZFYVE16

Spliceosome ( hsa03040 ):

SRSF10, HNRNPA3, SF3B1, U2SURP, TCERG1

Oocyte meiosis ( hsa04114 ):

CALM1, SLK, SMC1A, YWHAZ

Ubiquitin mediated proteolysis ( hsa04120 ):

CUL3, CUL5, UBR5, UBA3, UBE2J1

mTOR signaling pathway ( hsa04150 ):

CAB39

Wnt signaling pathway ( hsa04310 ):

FZD6, ROCK1, TBL1XR1

TGF-beta signaling pathway ( hsa04350 ):

ROCK1, ZFYVE16

Focal adhesion ( hsa04510 ):

ROCK1

RIG-I-like receptor signaling pathway ( hsa04622 ):

DDX3X

Neurotrophin signaling pathway ( hsa04722 ):

CALM1, YWHAZ

Regulation of actin cytoskeleton ( hsa04810 ):

PIKFYVE, RDX, ROCK1

Insulin signaling pathway ( hsa04910 ):

CALM1

Pathways in cancer ( hsa05200 ):

FZD6

Colorectal cancer ( hsa05210 ):

FZD6

Glioma ( hsa05214 ):

CALM1