芯片介绍

hsa-miR-32 miRNA靶基因表达谱PCR芯片精心选 择了hsa-miR-32 miRNA 可能的88个靶基因，采用精心设计和反复验证过的引物，运用实时荧光PCR方法帮您寻找miRNA真正的靶基因。应用2块靶基因PCR芯片分别对实验组和对照组样品进行分析，寻找表达有差异的基因，即可确定该miRNA的靶基因。如果您需要更改miRNA靶基因列表中的基因，也可以联系我们。

基因功能分类

根据Gene Ontology功能数据库和KEGG生物通路数据库对88个靶基因进行分类。

transcription ( GO:0006350 ):

BAZ2B, BCLAF1, BZW1, CAND1, CHD9, COPS2, FRYL, HIPK1, HIPK3, JMJD1C, NAB1, NCOA3, NOTCH2, NR3C1, PAPOLA, PHF3, PHTF2, PSIP1, RCOR1, SIRT1, SP3, SUV420H1, TBL1XR1, ZMYND11, ZNF238

cell cycle ( GO:0007049 ):

CD2AP, CUL3, EIF4G2, ERBB2IP, NOTCH2, PAFAH1B1, PTP4A1, RAD21, PDS5A, SMC1A, STAG1, STAG2, TLK1, USP9X, VPS4B, ZMYND11, RAD21, SMC1A, STAG1, STAG2, YWHAZ

enzyme linked receptor protein signaling pathway ( GO:0007167 ):

EPS8, ERBB2IP, TOB1, USP9X, ZFYVE16

intracellular signaling cascade ( GO:0007242 ):

AKAP11, ARHGAP29, DNAJA1, G3BP2, HIPK1, NCOA3, NR3C1, PIKFYVE, RAB14, RAP1B, RAP2C, SMC1A, SRPK2, TLK1

small GTPase mediated signal transduction ( GO:0007264 ):

ARHGAP29, G3BP2, RAB14, RAP1B, RAP2C

protein localization ( GO:0008104 ):

ERBB2IP, EXOC5, G3BP2, LIN7C, MORC3, PIKFYVE, RAB14, RDX, SEC31A, SERP1, SNX2, TLK1, TOB1, VPS4B, YWHAZ, ZDHHC17, ZFYVE16

macromolecule catabolic process ( GO:0009057 ):

ADAM10, CAND1, CD2AP, CUL3, DCP2, FBXO28, FBXW2, RNF11, RNF138, TBL1XR1, THRB, UBE2G1, USP9X

negative regulation of biosynthetic process ( GO:0009890 ):

ATXN1, BCLAF1, COPS2, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, TIA1, ZMYND11, ZNF238

negative regulation of signal transduction ( GO:0009968 ):

ATXN1, SIRT1, STRN3, TOB1

negative regulation of macromolecule biosynthetic process ( GO:0010558 ):

ATXN1, BCLAF1, COPS2, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, TIA1, ZMYND11, ZNF238

negative regulation of macromolecule metabolic process ( GO:0010605 ):

ATXN1, BCLAF1, COPS2, SRSF10, IBTK, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, TIA1, ZMYND11, ZNF238

posttranscriptional regulation of gene expression ( GO:0010608 ):

EIF4G2, MORC3, PAIP1, QKI, SERBP1, TIA1

negative regulation of gene expression ( GO:0010629 ):

ATXN1, BCLAF1, COPS2, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, ZMYND11, ZNF238

negative regulation of cell communication ( GO:0010648 ):

ATXN1, SIRT1, STRN3, TOB1

protein transport ( GO:0015031 ):

ERBB2IP, EXOC5, LIN7C, RAB14, SEC31A, SERP1, SNX2, TLK1, TOB1, VPS4B, YWHAZ, ZDHHC17, ZFYVE16

mRNA metabolic process ( GO:0016071 ):

DCP2, SRSF10, PAIP1, PAPOLA, PRPF40A, SERBP1, SF3B1, SRSF11, SREK1, SCAF11, SRSF3, SMC1A, SRPK2

endosome transport ( GO:0016197 ):

PIKFYVE, VPS4B, ZFYVE16

negative regulation of transcription ( GO:0016481 ):

ATXN1, BCLAF1, COPS2, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, ZMYND11, ZNF238

modification-dependent protein catabolic process ( GO:0019941 ):

CAND1, CD2AP, CUL3, FBXO28, FBXW2, RNF11, RNF138, TBL1XR1, THRB, UBE2G1, USP9X

protein catabolic process ( GO:0030163 ):

ADAM10, CAND1, CD2AP, CUL3, FBXO28, FBXW2, RNF11, RNF138, TBL1XR1, THRB, UBE2G1, USP9X

steroid hormone receptor signaling pathway ( GO:0030518 ):

DNAJA1, NCOA3, NR3C1

androgen receptor signaling pathway ( GO:0030521 ):

DNAJA1, NCOA3

intracellular receptor-mediated signaling pathway ( GO:0030522 ):

DNAJA1, NCOA3, NR3C1

negative regulation of cellular biosynthetic process ( GO:0031327 ):

ATXN1, BCLAF1, COPS2, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, TIA1, ZMYND11, ZNF238

regulation of RNA stability ( GO:0043487 ):

PAIP1

regulation of mRNA stability ( GO:0043488 ):

PAIP1

RNA stabilization ( GO:0043489 ):

PAIP1

modification-dependent macromolecule catabolic process ( GO:0043632 ):

CAND1, CD2AP, CUL3, FBXO28, FBXW2, RNF11, RNF138, TBL1XR1, THRB, UBE2G1, USP9X

cellular protein catabolic process ( GO:0044257 ):

ADAM10, CAND1, CD2AP, CUL3, FBXO28, FBXW2, RNF11, RNF138, TBL1XR1, THRB, UBE2G1, USP9X

cellular macromolecule catabolic process ( GO:0044265 ):

ADAM10, CAND1, CD2AP, CUL3, DCP2, FBXO28, FBXW2, RNF11, RNF138, TBL1XR1, THRB, UBE2G1, USP9X

establishment of protein localization ( GO:0045184 ):

ERBB2IP, EXOC5, LIN7C, RAB14, SEC31A, SERP1, SNX2, TLK1, TOB1, VPS4B, YWHAZ, ZDHHC17, ZFYVE16

regulation of transcription ( GO:0045449 ):

AFF1, ATRX, ATXN1, BAZ2B, BCLAF1, BZW1, CAND1, CHD9, COPS2, FRYL, SRSF10, HIPK1, HIPK3, JMJD1C, MTDH, NAB1, NCOA3, NOTCH2, NR3C1, PHTF2, PSIP1, RCOR1, SIRT1, SP3, STRN3, SUV420H1, TBL1XR1, ZMYND11, ZNF238

negative regulation of transcription, DNA-dependent ( GO:0045892 ):

MTDH, SIRT1, STRN3, TBL1XR1, ZMYND11, ZNF238

positive regulation of transcription, DNA-dependent ( GO:0045893 ):

AFF1, ATXN1, CAND1, NCOA3, STRN3, TBL1XR1

negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic pro ( GO:0045934 ):

ATXN1, BCLAF1, COPS2, SRSF10, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, ZMYND11, ZNF238

intracellular transport ( GO:0046907 ):

ATXN1, ERBB2IP, EXOC5, SRSF10, KIF5B, PAFAH1B1, PIKFYVE, RAB14, SEC31A, SNX2, TLK1, TOB1, VPS4B, YWHAZ, ZFYVE16

mRNA stabilization ( GO:0048255 ):

PAIP1

negative regulation of nitrogen compound metabolic process ( GO:0051172 ):

ATXN1, BCLAF1, COPS2, SRSF10, MTDH, NAB1, SIRT1, STRN3, TBL1XR1, ZMYND11, ZNF238

negative regulation of RNA metabolic process ( GO:0051253 ):

SRSF10, MTDH, SIRT1, STRN3, TBL1XR1, ZMYND11, ZNF238

positive regulation of RNA metabolic process ( GO:0051254 ):

AFF1, ATXN1, CAND1, NCOA3, STRN3, TBL1XR1

cell division ( GO:0051301 ):

CD2AP, PAFAH1B1, RAD21, PDS5A, SMC1A, STAG1, STAG2, USP9X, VPS4B

proteolysis involved in cellular protein catabolic process ( GO:0051603 ):

ADAM10, CAND1, CD2AP, CUL3, FBXO28, FBXW2, RNF11, RNF138, TBL1XR1, THRB, UBE2G1, USP9X

Phosphatidylinositol signaling system ( hsa04070 ):

PIKFYVE

Oocyte meiosis ( hsa04114 ):

PPP2R5E, SMC1A, YWHAZ

Ubiquitin mediated proteolysis ( hsa04120 ):

CUL3, UBE2G1

TGF-beta signaling pathway ( hsa04350 ):

ZFYVE16

Focal adhesion ( hsa04510 ):

PPP1R12A, RAP1B

Long-term potentiation ( hsa04720 ):

PPP1R12A, RAP1B

Neurotrophin signaling pathway ( hsa04722 ):

RAP1B, YWHAZ

Regulation of actin cytoskeleton ( hsa04810 ):

PIKFYVE, PPP1R12A, RDX