芯片介绍

hsa-miR-520a-5p miRNA靶基因表达谱PCR芯片精心选 择了hsa-miR-520a-5p miRNA 可能的88个靶基因，采用精心设计和反复验证过的引物，运用实时荧光PCR方法帮您寻找miRNA真正的靶基因。应用2块靶基因PCR芯片分别对实验组和对照组样品进行分析，寻找表达有差异的基因，即可确定该miRNA的靶基因。如果您需要更改miRNA靶基因列表中的基因，也可以联系我们。

基因功能分类

根据Gene Ontology功能数据库和KEGG生物通路数据库对88个靶基因进行分类。

regionalization ( GO:0003002 ):

ALDH1A2, BTG2, HOXD10, TCF7L1

circulatory system process ( GO:0003013 ):

COL4A3, CYP11B1, DRD2, ELN, NPR3

regulation of systemic arterial blood pressure ( GO:0003073 ):

DRD2

immune response ( GO:0006955 ):

AQP9, C8A, CYP11B1, FASLG, FOXP1, GPSM3, IKBKG, LCP1, SEMA7A, SIT1

cell adhesion ( GO:0007155 ):

ADAM15, BMP1, CD84, CLCA2, CNTNAP2, COL4A3, HABP2, ITGA10, ITGA2B, ITGB3, MUC5AC, NCAM1, PDPK1, PECAM1, SIRPA, SSX2IP, THRA

cell surface receptor linked signal transduction ( GO:0007166 ):

ADCY1, ADCY2, ANGPT1, ATRNL1, COL4A3, DRD2, DTX4, EFNB3, EPHB2, FBXW11, FGF5, FGFR2, FZD4, GABRA1, GABRA4, GNAS, GRIK3, GRIN2B, HTR4, IKBKG, ITGA10, ITGA2B, ITGB3, LPHN1, MAPK14, NCAM1, NDP, NPR3, NTRK2, NTRK3, PML, PTGER3, RGS6, SEMA6A, SENP2, SORCS3, TCF7L1, WNT11

G-protein signaling, coupled to cyclic nucleotide second messenger ( GO:0007187 ):

ADCY1, ADCY2, GNAS, HTR4, NPR3, PTGER3

G-protein signaling, coupled to cAMP nucleotide second messenger ( GO:0007188 ):

ADCY1, ADCY2, GNAS, NPR3, PTGER3

activation of adenylate cyclase activity by G-protein signaling pathway ( GO:0007189 ):

ADCY1, ADCY2, GNAS

activation of adenylate cyclase activity ( GO:0007190 ):

ADCY1, ADCY2, GNAS, NTRK2

cell-cell signaling ( GO:0007267 ):

ASIC2, BSN, DLGAP2, DRD2, EFNB3, FASLG, FGF5, GRIN2B, NDP, NOS1, NOVA1, NTRK2, SCN2B

synaptic transmission ( GO:0007268 ):

ASIC2, BSN, DLGAP2, DRD2, GRIN2B, NOS1, NOVA1, SCN2B

behavior ( GO:0007610 ):

ADCY1, AFF2, EFNB3, EPHB2, GRIN2B, HOXD10, MAPK14, NHLH2, NOVA1, NTRK2

blood circulation ( GO:0008015 ):

COL4A3, CYP11B1, DRD2, ELN, NPR3

cell recognition ( GO:0008037 ):

CNTNAP2, EFNB3, PECAM1

anterior/posterior pattern formation ( GO:0009952 ):

ALDH1A2, BTG2, HOXD10, TCF7L1

regulation of adenylate cyclase activity involved in G-protein signaling ( GO:0010578 ):

ADCY1, ADCY2, GNAS

positive regulation of adenylate cyclase activity by G-protein signaling pathway ( GO:0010579 ):

ADCY1, ADCY2, GNAS

Wnt receptor signaling pathway ( GO:0016055 ):

FBXW11, FZD4, NDP, SENP2, TCF7L1, WNT11

cell-cell adhesion ( GO:0016337 ):

BMP1, CD84, NCAM1, THRA

transmission of nerve impulse ( GO:0019226 ):

ASIC2, BSN, CNTNAP2, DLGAP2, DRD2, GRIN2B, NOS1, NOVA1, SCN2B

cAMP-mediated signaling ( GO:0019933 ):

ADCY1, ADCY2, GNAS, NPR3, PTGER3

biological adhesion ( GO:0022610 ):

ADAM15, BMP1, CD84, CLCA2, CNTNAP2, COL4A3, HABP2, ITGA10, ITGA2B, ITGB3, MUC5AC, NCAM1, PDPK1, PECAM1, SIRPA, SSX2IP, THRA

water homeostasis ( GO:0030104 ):

AQP9, PTGER3

neuron differentiation ( GO:0030182 ):

ALDH1A2, BCL11B, BTG2, CNTNAP2, DCX, DRD2, EFNB3, EPHB2, GAS7, HOXD10, KIF5C, NTRK2, NTRK3, POU4F2, RTN1, SEMA6A

regulation of cAMP metabolic process ( GO:0030814 ):

ADCY1, ADCY2, GNAS, NPR3, NTRK2

regulation of cAMP biosynthetic process ( GO:0030817 ):

ADCY1, ADCY2, GNAS, NPR3, NTRK2

regulation of cyclase activity ( GO:0031279 ):

ADCY1, ADCY2, GNAS, NPR3, NTRK2

regulation of system process ( GO:0044057 ):

CPS1, DRD2, EPHB2, GRIK3, GRIN2B, NOS1, NTRK2, PPP1R12B, SNCAIP, THRA, TNNI1

regulation of adenylate cyclase activity ( GO:0045761 ):

ADCY1, ADCY2, GNAS, NPR3, NTRK2

rhythmic process ( GO:0048511 ):

ANGPT1, BCL2L1, DRD2, GRIN2B, NHLH2, PER1

embryonic morphogenesis ( GO:0048598 ):

ALDH1A2, GNAS, HOXD10, PRRX1

neuron development ( GO:0048666 ):

BCL11B, CNTNAP2, DCX, EFNB3, EPHB2, GAS7, HOXD10, KIF5C, NTRK2, POU4F2, SEMA6A

embryonic cranial skeleton morphogenesis ( GO:0048701 ):

GNAS

skeletal system morphogenesis ( GO:0048705 ):

BMP1, GNAS, HOXD10, PRRX1, THRA

regulation of lyase activity ( GO:0051339 ):

ADCY1, ADCY2, GNAS, NPR3, NTRK2

Steroid hormone biosynthesis ( hsa00140 ):

CYP11B1

Calcium signaling pathway ( hsa04020 ):

ADCY1, ADCY2, GNAS, HTR4, PTGER3

Cytokine-cytokine receptor interaction ( hsa04060 ):

CSF1, FASLG, IL10RA

Neuroactive ligand-receptor interaction ( hsa04080 ):

GABRA1, GABRA4, GRIK3, GRIN2B, HTR4, PTGER3, THRA

Wnt signaling pathway ( hsa04310 ):

FBXW11, FZD4, SENP2, TCF7L1, WNT11

Hedgehog signaling pathway ( hsa04340 ):

FBXW11, WNT11

Axon guidance ( hsa04360 ):

EFNB3, EPHB2, SEMA6D, SEMA7A

Cell adhesion molecules (CAMs) ( hsa04514 ):

CNTNAP2, NCAM1, PECAM1

T cell receptor signaling pathway ( hsa04660 ):

IKBKG, MAPK14

Melanogenesis ( hsa04916 ):

ADCY1, ADCY2, FZD4, GNAS, TCF7L1, WNT11

Pathways in cancer ( hsa05200 ):

BCL2L1, FASLG, FGF5, FGFR2, FZD4, IKBKG, ITGA2B, PML, RXRB, TCF7L1, WNT11

Basal cell carcinoma ( hsa05217 ):

FZD4, TCF7L1, WNT11

Systemic lupus erythematosus ( hsa05322 ):

C8A, GRIN2B

Hypertrophic cardiomyopathy (HCM) ( hsa05410 ):

ITGA10, ITGA2B, ITGB3

Arrhythmogenic right ventricular cardiomyopathy (ARVC) ( hsa05412 ):

ITGA10, ITGA2B, ITGB3, TCF7L1

Dilated cardiomyopathy ( hsa05414 ):

ADCY1, ADCY2, GNAS, ITGA10, ITGA2B, ITGB3