芯片介绍
hsa-miR-9 miRNA靶基因表达谱PCR芯片精心选
择了hsa-miR-9 miRNA
可能的88个靶基因，采用精心设计和反复验证过的引物，运用实时荧光PCR方法帮您寻找miRNA真正的靶基因。应用2块靶基因PCR芯片分别对实验组和对照组样品进行分析，寻找表达有差异的基因，即可确定该miRNA的靶基因。如果您需要更改miRNA靶基因列表中的基因，也可以联系我们。
基因功能分类
根据Gene Ontology功能数据库和KEGG生物通路数据库对88个靶基因进行分类。
M phase of mitotic cell cycle ( GO:0000087 ):
CD2AP, PAFAH1B1, RAD21, PDS5A, SMC1A
mitotic cell cycle ( GO:0000278 ):
CD2AP, CUL5, PAFAH1B1, PPP3CA, RAD21, PDS5A, SMC1A
nuclear division ( GO:0000280 ):
CD2AP, PAFAH1B1, RAD21, PDS5A, SMC1A
RNA splicing, via transesterification reactions ( GO:0000375 ):
HNRNPA3, MBNL1, SRSF1, SMC1A
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile ( GO:0000377 ):
HNRNPA3, MBNL1, SRSF1, SMC1A
nuclear mRNA splicing, via spliceosome ( GO:0000398 ):
HNRNPA3, MBNL1, SRSF1, SMC1A
vasculature development ( GO:0001944 ):
DICER1, QKI, RASA1, RBPJ, VEZF1
chromatin organization ( GO:0006325 ):
ARID4B, CBX1, HLTF, NAP1L1, TBL1XR1, TLK1
transcription ( GO:0006350 ):
ARID4B, ATF1, ATF2, BCLAF1, COPS2, DR1, HLTF, NAB1, PURA, RB1CC1, RBPJ, RYBP, SMAD4, TBL1XR1, TROVE2, VEZF1, ZBTB1
regulation of transcription from RNA polymerase II promoter ( GO:0006357 ):
DR1, HLTF, PRKAR1A, RYBP, SMAD4, TBL1XR1, VEZF1
RNA processing ( GO:0006396 ):
DICER1, HNRNPA3, MBNL1, QKI, SRSF1, SMC1A, U2SURP, SYNCRIP
mRNA processing ( GO:0006397 ):
HNRNPA3, MBNL1, QKI, SRSF1, SMC1A, SYNCRIP
RNA localization ( GO:0006403 ):
FMR1, QKI, RANBP2
protein amino acid dephosphorylation ( GO:0006470 ):
PPP3CA, PTPN11
ubiquitin-dependent protein catabolic process ( GO:0006511 ):
CD2AP, CUL5, UBR5, PCNP, RNF11, TBL1XR1, UBE2D3, USP1
protein targeting ( GO:0006605 ):
ERBB2IP, PPP3CA, RANBP2, SEC62, TRAM1, ZFYVE16
intracellular protein transport ( GO:0006886 ):
ERBB2IP, PPP3CA, RANBP2, TLK1, SEC62, TRAM1, ZFYVE16
nucleocytoplasmic transport ( GO:0006913 ):
PPP3CA, RANBP2
apoptosis ( GO:0006915 ):
BNIP3L, RAD21, RHOT1, RYBP, SLK
induction of apoptosis ( GO:0006917 ):
BCLAF1, BNIP3L, CUL5
cell cycle ( GO:0007049 ):
ATR, CALM1, CD2AP, CUL5, DST, ERBB2IP, PAFAH1B1, PCNP, PPP3CA, RAD21, RB1CC1, PDS5A, SEPT10, SMC1A, TLK1
mitotic spindle organization ( GO:0007052 ):
SMC1A
mitosis ( GO:0007067 ):
CD2AP, PAFAH1B1, RAD21, PDS5A, SMC1A
enzyme linked receptor protein signaling pathway ( GO:0007167 ):
ABI1, EPS15, ERBB2IP, JAK1, PDGFC, PTPN11, SMAD4, UBE2D3, ZFYVE16
transmembrane receptor protein tyrosine kinase signaling pathway ( GO:0007169 ):
ABI1, EPS15, ERBB2IP, PDGFC, PTPN11
intracellular signaling cascade ( GO:0007242 ):
AKAP11, ATR, UBR5, JAK1, PIK3C2A, PRKAR1A, PRKD3, PTPN11, RAB14, RAB21, RAP1B, RAPGEF2, RASA1, RB1CC1, RHOT1, SMC1A, TLK1, WSB1
small GTPase mediated signal transduction ( GO:0007264 ):
RAB14, RAB21, RAP1B, RAPGEF2, RHOT1
protein localization ( GO:0008104 ):
CHMP2B, EPS15, ERBB2IP, PPP3CA, RAB14, RAB21, RANBP2, SEC31A, SNAP23, STXBP3, TLK1, SEC62, TRAM1, VPS13C, ZDHHC17, ZFYVE16
cell death ( GO:0008219 ):
BNIP3L, RAD21, RHOT1, RYBP, SLK
RNA splicing ( GO:0008380 ):
HNRNPA3, MBNL1, QKI, SRSF1, SMC1A, SYNCRIP
macromolecule catabolic process ( GO:0009057 ):
CD2AP, CUL5, DCP2, UBR5, FBXW2, HLTF, PCNP, PJA2, RANBP2, RNF11, RNF6, UBA2, TBL1XR1, UBE2D3, USP1, WSB1
negative regulation of biosynthetic process ( GO:0009890 ):
ATR, BCLAF1, COPS2, CTBP2, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of biosynthetic process ( GO:0009891 ):
AFF1, PDGFC, RNF6, SMAD4, TBL1XR1
positive regulation of macromolecule biosynthetic process ( GO:0010557 ):
AFF1, PDGFC, RNF6, SMAD4, TBL1XR1
negative regulation of macromolecule biosynthetic process ( GO:0010558 ):
ATR, BCLAF1, COPS2, CTBP2, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of macromolecule metabolic process ( GO:0010604 ):
AFF1, PDGFC, RB1CC1, RNF6, SMAD4, TBL1XR1
negative regulation of macromolecule metabolic process ( GO:0010605 ):
ATR, BCLAF1, BNIP3L, COPS2, CTBP2, DICER1, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of gene expression ( GO:0010628 ):
AFF1, RNF6, SMAD4, TBL1XR1
negative regulation of gene expression ( GO:0010629 ):
BCLAF1, BNIP3L, COPS2, CTBP2, DICER1, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
regulation of cell death ( GO:0010941 ):
BCLAF1, BNIP3L, CUL5, RASA1, RB1CC1, SON
positive regulation of cell death ( GO:0010942 ):
BCLAF1, BNIP3L, CUL5
programmed cell death ( GO:0012501 ):
BNIP3L, RAD21, RHOT1, RYBP, SLK
induction of programmed cell death ( GO:0012502 ):
BCLAF1, BNIP3L, CUL5
protein transport ( GO:0015031 ):
CHMP2B, EPS15, ERBB2IP, PPP3CA, RAB14, RAB21, RANBP2, SEC31A, SNAP23, STXBP3, TLK1, SEC62, TRAM1, ZDHHC17, ZFYVE16
nucleobase, nucleoside, nucleotide and nucleic acid transport ( GO:0015931 ):
FMR1, QKI, RANBP2
membrane organization ( GO:0016044 ):
PAFAH1B1, SEC31A, SNAP23, VAMP3
vesicle organization ( GO:0016050 ):
EPS15, ZFYVE16
mRNA metabolic process ( GO:0016071 ):
DCP2, HNRNPA3, MBNL1, QKI, SERBP1, SRSF1, SMC1A, SYNCRIP
vesicle-mediated transport ( GO:0016192 ):
ARFGEF1, RAB14, SEC31A, SNAP23, STXBP3, VAMP3, ZFYVE16
death ( GO:0016265 ):
BNIP3L, RAD21, RHOT1, RYBP, SLK
dephosphorylation ( GO:0016311 ):
PPP3CA, PTPN11, SACM1L
negative regulation of transcription ( GO:0016481 ):
BCLAF1, COPS2, CTBP2, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
protein ubiquitination ( GO:0016567 ):
PCNP, RNF11, UBE2D3
chromatin modification ( GO:0016568 ):
HLTF, TBL1XR1, TLK1
modification-dependent protein catabolic process ( GO:0019941 ):
CD2AP, CUL5, UBR5, FBXW2, HLTF, PCNP, PJA2, RANBP2, RNF11, RNF6, UBA2, TBL1XR1, UBE2D3, USP1, WSB1
cell cycle process ( GO:0022402 ):
CD2AP, CUL5, DST, PAFAH1B1, PPP3CA, RAD21, PDS5A, SMC1A
cell cycle phase ( GO:0022403 ):
CD2AP, CUL5, PAFAH1B1, PPP3CA, RAD21, PDS5A, SMC1A
protein catabolic process ( GO:0030163 ):
CD2AP, CUL5, UBR5, FBXW2, HLTF, PCNP, PJA2, RANBP2, RNF11, RNF6, UBA2, TBL1XR1, UBE2D3, USP1, WSB1
steroid hormone receptor signaling pathway ( GO:0030518 ):
UBR5
negative regulation of cellular biosynthetic process ( GO:0031327 ):
ATR, BCLAF1, COPS2, CTBP2, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of cellular biosynthetic process ( GO:0031328 ):
AFF1, PDGFC, RNF6, SMAD4, TBL1XR1
protein modification by small protein conjugation ( GO:0032446 ):
PCNP, RNF11, UBE2D3
cellular response to hormone stimulus ( GO:0032870 ):
PRKAR1A, PTPN11
cellular protein localization ( GO:0034613 ):
ERBB2IP, PPP3CA, RANBP2, TLK1, SEC62, TRAM1, ZFYVE16
regulation of apoptosis ( GO:0042981 ):
BCLAF1, BNIP3L, CUL5, RASA1, RB1CC1, SON
positive regulation of apoptosis ( GO:0043065 ):
BCLAF1, BNIP3L, CUL5
negative regulation of apoptosis ( GO:0043066 ):
BNIP3L, RASA1, RB1CC1, SON
regulation of programmed cell death ( GO:0043067 ):
BCLAF1, BNIP3L, CUL5, RASA1, RB1CC1, SON
positive regulation of programmed cell death ( GO:0043068 ):
BCLAF1, BNIP3L, CUL5
negative regulation of programmed cell death ( GO:0043069 ):
BNIP3L, RASA1, RB1CC1, SON
modification-dependent macromolecule catabolic process ( GO:0043632 ):
CD2AP, CUL5, UBR5, FBXW2, HLTF, PCNP, PJA2, RANBP2, RNF11, RNF6, UBA2, TBL1XR1, UBE2D3, USP1, WSB1
cellular protein catabolic process ( GO:0044257 ):
CD2AP, CUL5, UBR5, FBXW2, HLTF, PCNP, PJA2, RANBP2, RNF11, RNF6, UBA2, TBL1XR1, UBE2D3, USP1, WSB1
cellular macromolecule catabolic process ( GO:0044265 ):
CD2AP, CUL5, DCP2, UBR5, FBXW2, HLTF, PCNP, PJA2, RANBP2, RNF11, RNF6, UBA2, TBL1XR1, UBE2D3, USP1, WSB1
establishment of protein localization ( GO:0045184 ):
CHMP2B, EPS15, ERBB2IP, PPP3CA, RAB14, RAB21, RANBP2, SEC31A, SNAP23, STXBP3, TLK1, SEC62, TRAM1, ZDHHC17, ZFYVE16
regulation of transcription ( GO:0045449 ):
AFF1, ARID4B, ATF1, ATF2, BCLAF1, COPS2, CTBP2, DR1, HLTF, NAB1, PRKAR1A, PURA, RB1CC1, RBPJ, RNF6, RYBP, SMAD4, TBL1XR1, VEZF1, ZBTB1
negative regulation of transcription, DNA-dependent ( GO:0045892 ):
CTBP2, DR1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of transcription, DNA-dependent ( GO:0045893 ):
AFF1, RNF6, SMAD4, TBL1XR1
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic pro ( GO:0045934 ):
ATR, BCLAF1, COPS2, CTBP2, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic pro ( GO:0045935 ):
AFF1, PDGFC, RNF6, SMAD4, TBL1XR1
positive regulation of transcription ( GO:0045941 ):
AFF1, RNF6, SMAD4, TBL1XR1
positive regulation of transcription from RNA polymerase II promoter ( GO:0045944 ):
SMAD4, TBL1XR1
intracellular transport ( GO:0046907 ):
DST, ERBB2IP, PAFAH1B1, PPP3CA, RAB14, RANBP2, RHOT1, SEC31A, SNAP23, TLK1, SEC62, TRAM1, ZFYVE16
organelle fission ( GO:0048285 ):
CD2AP, PAFAH1B1, RAD21, PDS5A, SMC1A
nucleic acid transport ( GO:0050657 ):
FMR1, QKI, RANBP2
RNA transport ( GO:0050658 ):
FMR1, QKI, RANBP2
mRNA transport ( GO:0051028 ):
FMR1, RANBP2
nuclear transport ( GO:0051169 ):
PPP3CA, RANBP2
negative regulation of nitrogen compound metabolic process ( GO:0051172 ):
ATR, BCLAF1, COPS2, CTBP2, DR1, NAB1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of nitrogen compound metabolic process ( GO:0051173 ):
AFF1, PDGFC, RNF6, SMAD4, TBL1XR1
establishment of RNA localization ( GO:0051236 ):
FMR1, QKI, RANBP2
negative regulation of RNA metabolic process ( GO:0051253 ):
CTBP2, DR1, PURA, RBPJ, RYBP, SMAD4, TBL1XR1
positive regulation of RNA metabolic process ( GO:0051254 ):
AFF1, RNF6, SMAD4, TBL1XR1
chromosome organization ( GO:0051276 ):
ARID4B, CBX1, HLTF, NAP1L1, SMC1A, TBL1XR1, TLK1
cell division ( GO:0051301 ):
CD2AP, PAFAH1B1, RAD21, RASA1, PDS5A, SEPT10, SMC1A
proteolysis involved in cellular protein catabolic process ( GO:0051603 ):
CD2AP, CUL5, UBR5, FBXW2, HLTF, PCNP, PJA2, RANBP2, RNF11, RNF6, UBA2, TBL1XR1, UBE2D3, USP1, WSB1
negative regulation of cell death ( GO:0060548 ):
BNIP3L, RASA1, RB1CC1, SON
protein modification by small protein conjugation or removal ( GO:0070647 ):
PCNP, RNF11, UBE2D3, USP1
cellular macromolecule localization ( GO:0070727 ):
ERBB2IP, PPP3CA, RANBP2, TLK1, SEC62, TRAM1, ZFYVE16
MAPK signaling pathway ( hsa04010 ):
ATF2, PPP3CA, RAP1B, RAPGEF2, RASA1
Oocyte meiosis ( hsa04114 ):
CALM1, PPP2R5E, PPP3CA, SLK, SMC1A
p53 signaling pathway ( hsa04115 ):
ATR
Ubiquitin mediated proteolysis ( hsa04120 ):
CUL5, UBR5, UBA2, UBE2D3
Endocytosis ( hsa04144 ):
CHMP2B, EPS15
Wnt signaling pathway ( hsa04310 ):
CSNK1A1, CTBP2, PPP2R5E, PPP3CA, TBL1XR1
Notch signaling pathway ( hsa04330 ):
CTBP2, RBPJ
Focal adhesion ( hsa04510 ):
PDGFC, PPP1R12A, RAP1B
Long-term potentiation ( hsa04720 ):
CALM1, PPP1R12A, PPP3CA
Neurotrophin signaling pathway ( hsa04722 ):
CALM1, PTPN11, RAP1B
Regulation of actin cytoskeleton ( hsa04810 ):
PDGFC, PPP1R12A
Insulin signaling pathway ( hsa04910 ):
CALM1, PRKAR1A
GnRH signaling pathway ( hsa04912 ):
CALM1
Pathways in cancer ( hsa05200 ):
CTBP2, JAK1, SMAD4
Colorectal cancer ( hsa05210 ):
SMAD4
Renal cell carcinoma ( hsa05211 ):
PTPN11, RAP1B
Prostate cancer ( hsa05215 ):
PDGFC
Chronic myeloid leukemia ( hsa05220 ):
CTBP2, PTPN11