基因信息:
基因名称:
cytochrome P450, family 1, subfamily A, polypeptide 2
物种:
NCBI 基因身份号(GeneID):
1544
官方基因符号(Symbol):
CYP1A2
曾用基因符号:
CP12|P3-450|P450(PA)

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008].

该基因有下列转录产物(transcript):
NM_000761.3
产品:
产品编号 检测的转录产物
EXPHS64385 NM_000761.3

说明:本公司表达谱PCR芯片产品使用该引物。