基因信息:
基因名称:
glyceraldehyde-3-phosphate dehydrogenase
物种:
NCBI 基因身份号(GeneID):
2597
官方基因符号(Symbol):
GAPDH
曾用基因符号:
G3PD|GAPD

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014].

该基因有下列转录产物(transcript):
NM_002046.3
产品:
产品编号 检测的转录产物
EXPHS17872 NM_002046.3

说明:本公司表达谱PCR芯片产品使用该引物。