基因信息:
基因名称:
insulin-like growth factor 2 receptor
物种:
NCBI 基因身份号(GeneID):
3482
官方基因符号(Symbol):
IGF2R
曾用基因符号:
CD222|CIMPR|M6P-R|MPR1|MPRI

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015].

该基因有下列转录产物(transcript):
NM_000876.2
产品:
产品编号 检测的转录产物
EXPHS128341 NM_000876.2

说明:本公司表达谱PCR芯片产品使用该引物。