基因信息:
基因名称:
interleukin 1, beta
物种:
NCBI 基因身份号(GeneID):
3553
官方基因符号(Symbol):
IL1B
曾用基因符号:
IL-1|IL1-BETA|IL1F2

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

该基因有下列转录产物(transcript):
NM_000576.2
产品:
产品编号 检测的转录产物
EXPHS98512 NM_000576.2

说明:本公司表达谱PCR芯片产品使用该引物。