基因信息:
基因名称:
interleukin 4
物种:
NCBI 基因身份号(GeneID):
3565
官方基因符号(Symbol):
IL4
曾用基因符号:
BCGF-1|BCGF1|BSF-1|BSF1|IL-4

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

该基因有下列转录产物(transcript):
NM_000589.2
NM_172348.1
产品:
产品编号 检测的转录产物
EXPHS6029109 NM_000589.2
EXPHS63922 NM_000589.2 NM_172348.1

说明:本公司表达谱PCR芯片产品使用该引物。