基因信息:
基因名称:
aryl hydrocarbon receptor nuclear translocator
物种:
NCBI 基因身份号(GeneID):
405
官方基因符号(Symbol):
ARNT
曾用基因符号:
HIF-1-beta|HIF-1beta|HIF1-beta|HIF1B|HIF1BETA|TANGO|bHLHe2

This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013].

该基因有下列转录产物(transcript):
NM_001197325.1
NM_001668.3
NM_178427.2
产品:
产品编号 检测的转录产物
EXPHS6055092 NM_001668.3
EXPHS119351 NM_001197325.1 NM_001668.3 NM_178427.2

说明:本公司表达谱PCR芯片产品使用该引物。