基因信息:
基因名称:
mitogen-activated protein kinase 9
物种:
NCBI 基因身份号(GeneID):
5601
官方基因符号(Symbol):
MAPK9
曾用基因符号:
JNK-55|JNK2|JNK2A|JNK2ALPHA|JNK2B|JNK2BETA|PRKM9|SAPK|SAPK1a|p54a|p54aSAPK

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008].

该基因有下列转录产物(transcript):
NM_001135044.1
NM_002752.4
NM_139068.2
NM_139069.2
NM_139070.2
产品:
产品编号 检测的转录产物
EXPHS6005426 NM_002752.4 NM_139068.2
EXPHS6005425 NM_139069.2 NM_139070.2
EXPHS100035 NM_001135044.1 NM_002752.4 NM_139068.2 NM_139069.2 NM_139070.2
EXPHS100047 NM_002752.4 NM_139068.2 NM_139069.2 NM_139070.2

说明:本公司表达谱PCR芯片产品使用该引物。