| 基因名称： | MAP-kinase activating death domain |
|---|---|
| 物种： | 人 |
| NCBI 基因身份号（GeneID): | 8567 |
| 官方基因符号(Symbol): | MADD |
| 曾用基因符号： | DENN|IG20|RAB3GEP |
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
| NM_001135943.1 |
| NM_001135944.1 |
| NM_003682.3 |
| NM_130470.2 |
| NM_130471.2 |
| NM_130472.2 |
| NM_130473.2 |
| NM_130474.2 |
| NM_130475.2 |
| NM_130476.2 |
| 产品编号 | 检测的转录产物 | |
|---|---|---|
| EXPHS6026709 | NM_001135943.1 NM_001135944.1 NM_003682.3 NM_130470.2 NM_130471.2 NM_130472.2 NM_130473.2 NM_130476.2 | |
| EXPHS6026714 | NM_001135943.1 NM_130475.2 NM_130476.2 | |
| EXPHS6026713 | NM_001135944.1 NM_003682.3 NM_130471.2 NM_130472.2 NM_130473.2 NM_130474.2 | |
| EXPHS6026704 | NM_003682.3 NM_130471.2 NM_130473.2 NM_130475.2 | |
| EXPHS6026712 | NM_130470.2 | |
| EXPHS63817 | NM_001135943.1 NM_001135944.1 NM_003682.3 NM_130470.2 NM_130471.2 NM_130472.2 NM_130473.2 NM_130474.2 NM_130475.2 NM_130476.2 |
说明：本公司表达谱PCR芯片产品使用该引物。